Integrated Tandem Electrochemical‐chemical‐electrochemical Coupling of Biomass and Nitrate to Sustainable Alanine

Alanine is widely employed for synthesizing polymers, pharmaceuticals, and agrochemicals. Electrocatalytic coupling of biomass molecules waste nitrate attractive the removal alanine production under ambient conditions. However, reaction efficiency relatively low due to activation stable substrates, two reactive intermediates remains challenging. Herein, we realize integrated tandem electrochemical‐chemical‐electochemical synthesis from biomass‐derived pyruvic acid (PA) (NO3‐) catalyzed by PdCu nano‐bead‐wires (PdCu NBWs). The overall pathway demonstrated as a multiple‐step catalytic cascade process via NH2OH PA on catalyst surface. Interestingly, in this electrochemical‐chemical‐electrochemical process, Cu facilitates electrochemical reduction intermediates, which chemically couple with form oxime, Pd promotes oxime desirable alanine. This work provides green strategy convert NO3‐ wealth enriches substrate scope renewable feedstocks produce high‐value amino acids.